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Wappapello Community Resources Wappapello Lake Area Association Wappapello Lake Association is a non-profit partner with the U.S. Army Corps of Engineers. This Association is committed to enhancing recreational activities, increasing tourism and promoting economic growth in the Wappapello Lake Area. Bill Emerson Memorial Visitor Center Bill Emerson Memorial Visitor Center (573) 222-8773 Directions & Lake History/Factoid Directions:  Southeast Missouri. From St. Louis, travel south 32 miles on I-55 to U.S. 67. Continue south 88 miles to Greenville. Turn left on Highway D, travel south 20 miles. Factoid:  Wappapello Lake, MO is a 45,000-acre project nestled in the foothills of the Ozark Mountains on the St. Francis River in Southeast Missouri. Completed in 1941, Wapppapello Lake annually provides an estimated $3.9 million in flood protection to agricultural lands and developed areas along the St. Francis River. In 1996, the mascot Ranger Willie B. Safe

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